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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CDK2/Cyclin A/Cyclin A1' and Ligand = 'BDBM50307537'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (Human))
BDBM50307537
PNG
(CHEMBL606409 | N-1-Dimethyl-8-{[1-(phenylcarbonyl)...)
Show SMILES CNC(=O)c1nn(C)c-2c1CCc1cnc(NC3CCN(CC3)C(=O)c3ccccc3)nc-21
Show InChI InChI=1S/C24H27N7O2/c1-25-22(32)20-18-9-8-16-14-26-24(28-19(16)21(18)30(2)29-20)27-17-10-12-31(13-11-17)23(33)15-6-4-3-5-7-15/h3-7,14,17H,8-13H2,1-2H3,(H,25,32)(H,26,27,28)
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PC cid
PC sid
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Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin A


J Med Chem 53: 2171-87 (2010)


Article DOI: 10.1021/jm901710h
BindingDB Entry DOI: 10.7270/Q2N879W9
More data for this
Ligand-Target Pair