Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'CREB-binding protein/Histone acetyltransferase p300' and Ligand = 'BDBM50200423'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein/Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50200423 (CHEMBL3911524) Show SMILES CC(=O)N1CCc2c(C1)c(Nc1cccc(c1)-c1cc[nH]n1)nn2CC1CC1 Show InChI InChI=1S/C21H24N6O/c1-14(28)26-10-8-20-18(13-26)21(25-27(20)12-15-5-6-15)23-17-4-2-3-16(11-17)19-7-9-22-24-19/h2-4,7,9,11,15H,5-6,8,10,12-13H2,1H3,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assay				J Med Chem 59: 10549-10563 (2016) Article DOI: 10.1021/acs.jmedchem.6b01022 BindingDB Entry DOI: 10.7270/Q27083DF
					More data for this Ligand-Target Pair
CREB-binding protein/Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50200423 (CHEMBL3911524) Show SMILES CC(=O)N1CCc2c(C1)c(Nc1cccc(c1)-c1cc[nH]n1)nn2CC1CC1 Show InChI InChI=1S/C21H24N6O/c1-14(28)26-10-8-20-18(13-26)21(25-27(20)12-15-5-6-15)23-17-4-2-3-16(11-17)19-7-9-22-24-19/h2-4,7,9,11,15H,5-6,8,10,12-13H2,1H3,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of Halo-tagged histone H3.3 binding to CBP/EP300 (unknown origin) expressed in HEK293 cells measured after overnight incubation by lucifer...				J Med Chem 59: 10549-10563 (2016) Article DOI: 10.1021/acs.jmedchem.6b01022 BindingDB Entry DOI: 10.7270/Q27083DF
					More data for this Ligand-Target Pair