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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM340503'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))		BDBM340503
PNG
(1-[3-[2-fluoro-4-[1-methyl-3-(trifluoromethyl)pyra...)
Show SMILES CC(=O)N1CCc2c(C1)c(Nc1ccc(cc1F)-c1cn(C)nc1C(F)(F)F)nn2C
Show InChI InChI=1S/C20H20F4N6O/c1-11(31)30-7-6-17-14(10-30)19(27-29(17)3)25-16-5-4-12(8-15(16)21)13-9-28(2)26-18(13)20(22,23)24/h4-5,8-9H,6-7,10H2,1-3H3,(H,25,27)
PDB
MMDB

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US Patent
n/an/a 10n/an/an/an/an/an/a



GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent


Assay Description
His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...

US Patent US9763922 (2017)


BindingDB Entry DOI: 10.7270/Q23N25G6
More data for this
Ligand-Target Pair