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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM340509'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))		BDBM340509
PNG
(US9763922, Example 40)
Show SMILES CC(=O)N1CCc2c(C1)c(Nc1cc(ccc1F)-c1cnn(C)c1)nn2CC1CC1
Show InChI InChI=1S/C22H25FN6O/c1-14(30)28-8-7-21-18(13-28)22(26-29(21)11-15-3-4-15)25-20-9-16(5-6-19(20)23)17-10-24-27(2)12-17/h5-6,9-10,12,15H,3-4,7-8,11,13H2,1-2H3,(H,25,26)
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US Patent
n/an/a 10n/an/an/an/an/an/a



GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent


Assay Description
His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...

US Patent US9763922 (2017)


BindingDB Entry DOI: 10.7270/Q23N25G6
More data for this
Ligand-Target Pair