Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM340745'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein (Homo sapiens (Human))	BDBM340745 (US9763922, Example 271) Show SMILES CNC(=O)N1CCc2c(C1)c(Nc1cc(cc(c1)S(=O)(=O)N(C)C)-c1cnn(C)c1)nn2C1CCOCC1 Show InChI InChI=1S/C25H34N8O4S/c1-26-25(34)32-8-5-23-22(16-32)24(29-33(23)20-6-9-37-10-7-20)28-19-11-17(18-14-27-31(4)15-18)12-21(13-19)38(35,36)30(2)3/h11-15,20H,5-10,16H2,1-4H3,(H,26,34)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...				US Patent US9763922 (2017) BindingDB Entry DOI: 10.7270/Q23N25G6
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