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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CVF-Bb Complex' and Ligand = 'BDBM251381'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251381
PNG
(US9452990, 61)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(C[C@@H]1C)C(=O)C[C@@H](N)c1ccc(cc1)C(F)(F)F |r|
Show InChI InChI=1/C25H28F4N6O3/c1-13-12-34(19(36)11-17(30)14-4-6-15(7-5-14)25(27,28)29)8-9-35(13)24-32-21-16(23(31)33-24)10-18(37-2)22(38-3)20(21)26/h4-7,10,13,17H,8-9,11-12,30H2,1-3H3,(H2,31,32,33)/t13-,17+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/a7.425



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9452990 (2016)

More data for this
Ligand-Target Pair