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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CVF-Bb Complex' and Ligand = 'BDBM251404'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251404
PNG
(US9452990, 86)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](N(C)C)c1ccc(F)cc1 |r|
Show InChI InChI=1/C25H30F2N6O3/c1-31(2)18(15-5-7-16(26)8-6-15)14-20(34)32-9-11-33(12-10-32)25-29-22-17(24(28)30-25)13-19(35-3)23(36-4)21(22)27/h5-8,13,18H,9-12,14H2,1-4H3,(H2,28,29,30)/t18-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/a7.425



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9452990 (2016)

More data for this
Ligand-Target Pair