BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CVF-Bb Complex' and Ligand = 'BDBM251407'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251407
PNG
(US9452990, 89)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](NC(C)C)c1ccc(F)cc1 |r|
Show InChI InChI=1/C26H32F2N6O3/c1-15(2)30-19(16-5-7-17(27)8-6-16)14-21(35)33-9-11-34(12-10-33)26-31-23-18(25(29)32-26)13-20(36-3)24(37-4)22(23)28/h5-8,13,15,19,30H,9-12,14H2,1-4H3,(H2,29,31,32)/t19-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/a7.425



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9452990 (2016)

More data for this
Ligand-Target Pair