Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1' and Ligand = 'BDBM50217489'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217489 ((R)-N-(1-(cyclopropylmethyl)-2-oxoazepan-3-yl)-4-(...) Show SMILES O=C(N[C@@H]1CCCCN(CC2CC2)C1=O)N1CCC(CC1)N1Cc2ccccc2NC1=O Show InChI InChI=1S/C24H33N5O3/c30-22-21(7-3-4-12-28(22)15-17-8-9-17)26-23(31)27-13-10-19(11-14-27)29-16-18-5-1-2-6-20(18)25-24(29)32/h1-2,5-6,17,19,21H,3-4,7-16H2,(H,25,32)(H,26,31)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human CL receptor in RAMP1 membranes				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217489 ((R)-N-(1-(cyclopropylmethyl)-2-oxoazepan-3-yl)-4-(...) Show SMILES O=C(N[C@@H]1CCCCN(CC2CC2)C1=O)N1CCC(CC1)N1Cc2ccccc2NC1=O Show InChI InChI=1S/C24H33N5O3/c30-22-21(7-3-4-12-28(22)15-17-8-9-17)26-23(31)27-13-10-19(11-14-27)29-16-18-5-1-2-6-20(18)25-24(29)32/h1-2,5-6,17,19,21H,3-4,7-16H2,(H,25,32)(H,26,31)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP production				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair