Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1' and Ligand = 'BDBM50217491'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217491 ((cis racemic)-N-((3R)-1-(cyclopropylmethyl)-2-oxo-...) Show SMILES O=C(NC1CC(CCN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)n1nc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C30H36N6O3/c37-28-26(19-24(22-7-3-1-4-8-22)13-16-35(28)20-21-11-12-21)31-29(38)34-17-14-25(15-18-34)36-30(39)32-27(33-36)23-9-5-2-6-10-23/h1-10,21,24-26H,11-20H2,(H,31,38)(H,32,33,39)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	266	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human CL receptor in RAMP1 membranes				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217491 ((cis racemic)-N-((3R)-1-(cyclopropylmethyl)-2-oxo-...) Show SMILES O=C(NC1CC(CCN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)n1nc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C30H36N6O3/c37-28-26(19-24(22-7-3-1-4-8-22)13-16-35(28)20-21-11-12-21)31-29(38)34-17-14-25(15-18-34)36-30(39)32-27(33-36)23-9-5-2-6-10-23/h1-10,21,24-26H,11-20H2,(H,31,38)(H,32,33,39)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	266	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human CL receptor in RAMP1 membranes				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217491 ((cis racemic)-N-((3R)-1-(cyclopropylmethyl)-2-oxo-...) Show SMILES O=C(NC1CC(CCN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)n1nc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C30H36N6O3/c37-28-26(19-24(22-7-3-1-4-8-22)13-16-35(28)20-21-11-12-21)31-29(38)34-17-14-25(15-18-34)36-30(39)32-27(33-36)23-9-5-2-6-10-23/h1-10,21,24-26H,11-20H2,(H,31,38)(H,32,33,39)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	488	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP production				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217491 ((cis racemic)-N-((3R)-1-(cyclopropylmethyl)-2-oxo-...) Show SMILES O=C(NC1CC(CCN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)n1nc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C30H36N6O3/c37-28-26(19-24(22-7-3-1-4-8-22)13-16-35(28)20-21-11-12-21)31-29(38)34-17-14-25(15-18-34)36-30(39)32-27(33-36)23-9-5-2-6-10-23/h1-10,21,24-26H,11-20H2,(H,31,38)(H,32,33,39)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	488	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP production				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair