Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor' and Ligand = 'BDBM50224414'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50224414 (4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl...) Show SMILES O=C(N[C@@H]1CC[C@H](CNC1=O)c1ccccc1)N1CCC(CC1)n1c2cccnc2[nH]c1=O Show InChI InChI=1S/C24H28N6O3/c31-22-19(9-8-17(15-26-22)16-5-2-1-3-6-16)27-23(32)29-13-10-18(11-14-29)30-20-7-4-12-25-21(20)28-24(30)33/h1-7,12,17-19H,8-11,13-15H2,(H,26,31)(H,27,32)(H,25,28,33)/t17-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGPR from human CL receptor expressed in HEK293 cells				J Med Chem 50: 5564-7 (2007) Article DOI: 10.1021/jm070668p BindingDB Entry DOI: 10.7270/Q28C9W02
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50224414 (4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl...) Show SMILES O=C(N[C@@H]1CC[C@H](CNC1=O)c1ccccc1)N1CCC(CC1)n1c2cccnc2[nH]c1=O Show InChI InChI=1S/C24H28N6O3/c31-22-19(9-8-17(15-26-22)16-5-2-1-3-6-16)27-23(32)29-13-10-18(11-14-29)30-20-7-4-12-25-21(20)28-24(30)33/h1-7,12,17-19H,8-11,13-15H2,(H,26,31)(H,27,32)(H,25,28,33)/t17-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stimulated cAMP production				J Med Chem 50: 5564-7 (2007) Article DOI: 10.1021/jm070668p BindingDB Entry DOI: 10.7270/Q28C9W02
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50224414 (4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl...) Show SMILES O=C(N[C@@H]1CC[C@H](CNC1=O)c1ccccc1)N1CCC(CC1)n1c2cccnc2[nH]c1=O Show InChI InChI=1S/C24H28N6O3/c31-22-19(9-8-17(15-26-22)16-5-2-1-3-6-16)27-23(32)29-13-10-18(11-14-29)30-20-7-4-12-25-21(20)28-24(30)33/h1-7,12,17-19H,8-11,13-15H2,(H,26,31)(H,27,32)(H,25,28,33)/t17-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stimulated cAMP production in presence of 50% human serum				J Med Chem 50: 5564-7 (2007) Article DOI: 10.1021/jm070668p BindingDB Entry DOI: 10.7270/Q28C9W02
					More data for this Ligand-Target Pair