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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292493'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292493
PNG
((S)-N-(2-(diethylamino)propyl)-2-(3-(methylsulfony...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(C1)S(C)(=O)=O |r|
Show InChI InChI=1S/C27H33N7O3S2/c1-5-32(6-2)18(3)14-28-27(35)19-12-23(30-25(13-19)33-16-20(17-33)39(4,36)37)21-15-29-34-10-9-22(31-26(21)34)24-8-7-11-38-24/h7-13,15,18,20H,5-6,14,16-17H2,1-4H3,(H,28,35)/t18-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.140n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292493
PNG
((S)-N-(2-(diethylamino)propyl)-2-(3-(methylsulfony...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(C1)S(C)(=O)=O |r|
Show InChI InChI=1S/C27H33N7O3S2/c1-5-32(6-2)18(3)14-28-27(35)19-12-23(30-25(13-19)33-16-20(17-33)39(4,36)37)21-15-29-34-10-9-22(31-26(21)34)24-8-7-11-38-24/h7-13,15,18,20H,5-6,14,16-17H2,1-4H3,(H,28,35)/t18-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 31.3n/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair