Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292526'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292526 ((S)-N-(2-(diethylamino)propyl)-2-(3-(ethylsulfonam...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(C1)NS(=O)(=O)CC |r| Show InChI InChI=1S/C28H36N8O3S2/c1-5-34(6-2)19(4)15-29-28(37)20-13-24(31-26(14-20)35-17-21(18-35)33-41(38,39)7-3)22-16-30-36-11-10-23(32-27(22)36)25-9-8-12-40-25/h8-14,16,19,21,33H,5-7,15,17-18H2,1-4H3,(H,29,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292526 ((S)-N-(2-(diethylamino)propyl)-2-(3-(ethylsulfonam...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(C1)NS(=O)(=O)CC |r| Show InChI InChI=1S/C28H36N8O3S2/c1-5-34(6-2)19(4)15-29-28(37)20-13-24(31-26(14-20)35-17-21(18-35)33-41(38,39)7-3)22-16-30-36-11-10-23(32-27(22)36)25-9-8-12-40-25/h8-14,16,19,21,33H,5-7,15,17-18H2,1-4H3,(H,29,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	25.7	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair