Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292586'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292586 ((S)-N-(2-(diethylamino)propyl)-2-((2-sulfamoylethy...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(NCCS(N)(=O)=O)nc(c1)-c1cnn2ccc(nc12)-c1cccs1 |r| Show InChI InChI=1S/C25H32N8O3S2/c1-4-32(5-2)17(3)15-28-25(34)18-13-21(30-23(14-18)27-9-12-38(26,35)36)19-16-29-33-10-8-20(31-24(19)33)22-7-6-11-37-22/h6-8,10-11,13-14,16-17H,4-5,9,12,15H2,1-3H3,(H,27,30)(H,28,34)(H2,26,35,36)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292586 ((S)-N-(2-(diethylamino)propyl)-2-((2-sulfamoylethy...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(NCCS(N)(=O)=O)nc(c1)-c1cnn2ccc(nc12)-c1cccs1 |r| Show InChI InChI=1S/C25H32N8O3S2/c1-4-32(5-2)17(3)15-28-25(34)18-13-21(30-23(14-18)27-9-12-38(26,35)36)19-16-29-33-10-8-20(31-24(19)33)22-7-6-11-37-22/h6-8,10-11,13-14,16-17H,4-5,9,12,15H2,1-3H3,(H,27,30)(H,28,34)(H2,26,35,36)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	232	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair