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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292587'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292587
PNG
(N-((S)-2-(diethylamino)propyl)-2-((3S,4S)-3,4-dihy...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1C[C@H](O)[C@@H](O)C1 |r|
Show InChI InChI=1S/C27H33N7O3S/c1-4-32(5-2)17(3)13-28-27(37)18-11-21(30-25(12-18)33-15-22(35)23(36)16-33)19-14-29-34-9-8-20(31-26(19)34)24-7-6-10-38-24/h6-12,14,17,22-23,35-36H,4-5,13,15-16H2,1-3H3,(H,28,37)/t17-,22-,23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.140n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292587
PNG
(N-((S)-2-(diethylamino)propyl)-2-((3S,4S)-3,4-dihy...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1C[C@H](O)[C@@H](O)C1 |r|
Show InChI InChI=1S/C27H33N7O3S/c1-4-32(5-2)17(3)13-28-27(37)18-11-21(30-25(12-18)33-15-22(35)23(36)16-33)19-14-29-34-9-8-20(31-26(19)34)24-7-6-10-38-24/h6-12,14,17,22-23,35-36H,4-5,13,15-16H2,1-3H3,(H,28,37)/t17-,22-,23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair