Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292616'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292616 (N-((S)-2-(diethylamino)propyl)-2-((R)-2-(hydroxyme...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CCC[C@@H]1CO |r| Show InChI InChI=1S/C28H35N7O2S/c1-4-33(5-2)19(3)16-29-28(37)20-14-24(31-26(15-20)34-11-6-8-21(34)18-36)22-17-30-35-12-10-23(32-27(22)35)25-9-7-13-38-25/h7,9-10,12-15,17,19,21,36H,4-6,8,11,16,18H2,1-3H3,(H,29,37)/t19-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292616 (N-((S)-2-(diethylamino)propyl)-2-((R)-2-(hydroxyme...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CCC[C@@H]1CO |r| Show InChI InChI=1S/C28H35N7O2S/c1-4-33(5-2)19(3)16-29-28(37)20-14-24(31-26(15-20)34-11-6-8-21(34)18-36)22-17-30-35-12-10-23(32-27(22)35)25-9-7-13-38-25/h7,9-10,12-15,17,19,21,36H,4-6,8,11,16,18H2,1-3H3,(H,29,37)/t19-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	45.9	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair