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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292637'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292637
PNG
(N-((S)-2-(diethylamino)propyl)-2-((S)-2-(morpholin...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@H]1C(=O)N1CCOCC1 |r|
Show InChI InChI=1S/C31H38N8O3S/c1-4-36(5-2)21(3)19-32-30(40)22-17-25(23-20-33-39-11-8-24(35-29(23)39)27-7-6-16-43-27)34-28(18-22)38-10-9-26(38)31(41)37-12-14-42-15-13-37/h6-8,11,16-18,20-21,26H,4-5,9-10,12-15,19H2,1-3H3,(H,32,40)/t21-,26-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.160n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292637
PNG
(N-((S)-2-(diethylamino)propyl)-2-((S)-2-(morpholin...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@H]1C(=O)N1CCOCC1 |r|
Show InChI InChI=1S/C31H38N8O3S/c1-4-36(5-2)21(3)19-32-30(40)22-17-25(23-20-33-39-11-8-24(35-29(23)39)27-7-6-16-43-27)34-28(18-22)38-10-9-26(38)31(41)37-12-14-42-15-13-37/h6-8,11,16-18,20-21,26H,4-5,9-10,12-15,19H2,1-3H3,(H,32,40)/t21-,26-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 21.3n/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair