Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292660'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292660 (N-((S)-2-(diethylamino)propyl)-2-((R)-3-hydroxypyr...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@@H](O)C1 |r| Show InChI InChI=1S/C27H33N7O2S/c1-4-32(5-2)18(3)15-28-27(36)19-13-23(30-25(14-19)33-10-8-20(35)17-33)21-16-29-34-11-9-22(31-26(21)34)24-7-6-12-37-24/h6-7,9,11-14,16,18,20,35H,4-5,8,10,15,17H2,1-3H3,(H,28,36)/t18-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292660 (N-((S)-2-(diethylamino)propyl)-2-((R)-3-hydroxypyr...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@@H](O)C1 |r| Show InChI InChI=1S/C27H33N7O2S/c1-4-32(5-2)18(3)15-28-27(36)19-13-23(30-25(14-19)33-10-8-20(35)17-33)21-16-29-34-11-9-22(31-26(21)34)24-7-6-12-37-24/h6-7,9,11-14,16,18,20,35H,4-5,8,10,15,17H2,1-3H3,(H,28,36)/t18-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human full length His-tagged CaMK2delta expressed in baculovirus using Biotin labelled STK1 as substrate after 1 hr in pres...				Citation and Details Article DOI: 10.1016/j.bmcl.2017.10.040 BindingDB Entry DOI: 10.7270/Q2930WR2
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292660 (N-((S)-2-(diethylamino)propyl)-2-((R)-3-hydroxypyr...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@@H](O)C1 |r| Show InChI InChI=1S/C27H33N7O2S/c1-4-32(5-2)18(3)15-28-27(36)19-13-23(30-25(14-19)33-10-8-20(35)17-33)21-16-29-34-11-9-22(31-26(21)34)24-7-6-12-37-24/h6-7,9,11-14,16,18,20,35H,4-5,8,10,15,17H2,1-3H3,(H,28,36)/t18-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	32.6	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair