Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292662'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292662 (2-((R)-3-aminopyrrolidin-1-yl)-N-((S)-2-(diethylam...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C27H34N8OS/c1-4-33(5-2)18(3)15-29-27(36)19-13-23(31-25(14-19)34-10-8-20(28)17-34)21-16-30-35-11-9-22(32-26(21)35)24-7-6-12-37-24/h6-7,9,11-14,16,18,20H,4-5,8,10,15,17,28H2,1-3H3,(H,29,36)/t18-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292662 (2-((R)-3-aminopyrrolidin-1-yl)-N-((S)-2-(diethylam...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C27H34N8OS/c1-4-33(5-2)18(3)15-29-27(36)19-13-23(31-25(14-19)34-10-8-20(28)17-34)21-16-30-35-11-9-22(32-26(21)35)24-7-6-12-37-24/h6-7,9,11-14,16,18,20H,4-5,8,10,15,17,28H2,1-3H3,(H,29,36)/t18-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	68.8	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair