Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcium-activated potassium channel subunit alpha-1 (Rattus norvegicus) | BDBM50347497 (CHEMBL384903) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Induction of BK channel mediated vasorelaxation activity in Kcl-induced contraction in Wistar rat aorta | Eur J Med Chem 43: 792-9 (2008) Article DOI: 10.1016/j.ejmech.2007.06.005 BindingDB Entry DOI: 10.7270/Q2JM2BVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium-activated potassium channel subunit alpha-1 (Rattus norvegicus) | BDBM50347497 (CHEMBL384903) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Pisa Curated by ChEMBL | Assay Description Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic a... | J Med Chem 51: 5085-92 (2008) Article DOI: 10.1021/jm701605f BindingDB Entry DOI: 10.7270/Q2R49S16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium-activated potassium channel subunit alpha-1 (Rattus norvegicus) | BDBM50347497 (CHEMBL384903) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Activation of BK channel in Wistar rat thoracic aorta assessed as relaxation of KCl-induced contraction | Eur J Med Chem 43: 2618-26 (2008) Article DOI: 10.1016/j.ejmech.2008.02.032 BindingDB Entry DOI: 10.7270/Q2WM1FMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium-activated potassium channel subunit alpha-1 (Homo sapiens (Human)) | BDBM50347497 (CHEMBL384903) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile tone | Bioorg Med Chem 17: 319-25 (2008) Article DOI: 10.1016/j.bmc.2008.10.068 BindingDB Entry DOI: 10.7270/Q2P84D59 | |||||||||||
More data for this Ligand-Target Pair |