BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium-dependent protein kinase 1' and Ligand = 'BDBM36348'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Calcium-dependent protein kinase 1 (Plasmodium Falciparum)	BDBM36348 ((4-{9-(3-Chloro-phenyl)-2-[2-(3H-imidazol-4-yl)-et...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	626	n/a	n/a	n/a	n/a	7.5	24
The Scripps Research Institute					Assay Description The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...				Nat Chem Biol 4: 347-56 (2008) Article DOI: 10.1038/nchembio.87 BindingDB Entry DOI: 10.7270/Q2TB1573
The Scripps Research Institute					More data for this Ligand-Target Pair
Calcium-dependent protein kinase 1 (Plasmodium Falciparum)	BDBM36348 ((4-{9-(3-Chloro-phenyl)-2-[2-(3H-imidazol-4-yl)-et...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	352	n/a	n/a	7.5	24
The Scripps Research Institute					Assay Description This parasite proliferation assay, a modification of published DNA intercalating fluorescent dye-based assay, was adapted to 384-well plate format an...				Nat Chem Biol 4: 347-56 (2008) Article DOI: 10.1038/nchembio.87 BindingDB Entry DOI: 10.7270/Q2TB1573
The Scripps Research Institute					More data for this Ligand-Target Pair