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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM143486'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM143486
PNG
(US9682955, 137)
Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)c1ccc2ncnc(NC3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C32H28Cl2N4/c33-25-11-6-22(7-12-25)31(23-8-13-26(34)14-9-23)24-10-15-30-29(20-24)32(36-21-35-30)37-27-16-18-38(19-17-27)28-4-2-1-3-5-28/h1-15,20-21,27,31H,16-19H2,(H,35,36,37)
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US Patent
n/an/an/an/a 2n/an/an/a27



Janssen Pharmaceutica NV

US Patent


Assay Description
The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...


US Patent US9682955 (2017)


BindingDB Entry DOI: 10.7270/Q2707ZM3
More data for this
Ligand-Target Pair