Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50432712 (AM4089 | CHEMBL2348473) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay | J Med Chem 56: 3904-21 (2013) Article DOI: 10.1021/jm4000775 BindingDB Entry DOI: 10.7270/Q2VQ3429 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50432712 (AM4089 | CHEMBL2348473) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 mins | J Med Chem 56: 3904-21 (2013) Article DOI: 10.1021/jm4000775 BindingDB Entry DOI: 10.7270/Q2VQ3429 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50432712 (AM4089 | CHEMBL2348473) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Partial agonist activity at human CB1 receptor transfected in HEK293 cells assessed as reduction in forskolin-stimulated cAMP accumulation after 30 m... | J Med Chem 56: 3904-21 (2013) Article DOI: 10.1021/jm4000775 BindingDB Entry DOI: 10.7270/Q2VQ3429 | |||||||||||
More data for this Ligand-Target Pair |