Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82141 (WIN 55212-2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.30 | -46.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM82141 (WIN 55212-2) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP-55,940 from human CB1 receptor expressed in CHO cell membrane after 90 mins by scintillation counting method | Bioorg Med Chem 24: 5291-5301 (2016) Article DOI: 10.1016/j.bmc.2016.08.055 BindingDB Entry DOI: 10.7270/Q2HT2SV1 | |||||||||||
More data for this Ligand-Target Pair |