Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50265621 (((1R,4S,5R)-4-(2,6-dimethoxy-4-(2-methyloctan-2-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 22.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Displacement of [3H]CP 55940 from human CB2 receptor in cell free system | Eur J Med Chem 46: 547-55 (2011) Article DOI: 10.1016/j.ejmech.2010.11.034 BindingDB Entry DOI: 10.7270/Q2CF9QCJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50265621 (((1R,4S,5R)-4-(2,6-dimethoxy-4-(2-methyloctan-2-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 22.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Binding affinity to CB2 receptor | J Med Chem 52: 369-78 (2009) Article DOI: 10.1021/jm801044g BindingDB Entry DOI: 10.7270/Q2VQ33M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50265621 (((1R,4S,5R)-4-(2,6-dimethoxy-4-(2-methyloctan-2-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 22.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen, Inc. Curated by ChEMBL | Assay Description Binding affinity to cannabinoid CB2 receptor | J Med Chem 53: 4332-53 (2010) Article DOI: 10.1021/jm9018756 BindingDB Entry DOI: 10.7270/Q21R6QPF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Rattus norvegicus (Rat)) | BDBM50265621 (((1R,4S,5R)-4-(2,6-dimethoxy-4-(2-methyloctan-2-yl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica Curated by ChEMBL | Assay Description Displacement of [3H]HU-243 from rat CB2 receptor expressed in African green monkey COS7 cell membranes after 90 mins | J Med Chem 59: 6753-6771 (2016) Article DOI: 10.1021/acs.jmedchem.6b00397 BindingDB Entry DOI: 10.7270/Q2Q243Q0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Rattus norvegicus (Rat)) | BDBM50265621 (((1R,4S,5R)-4-(2,6-dimethoxy-4-(2-methyloctan-2-yl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica Curated by ChEMBL | Assay Description Displacement of [3H]HU-243 from rat CB2 receptor expressed in African green monkey COS7 cell membranes after 90 mins | J Med Chem 59: 6753-6771 (2016) Article DOI: 10.1021/acs.jmedchem.6b00397 BindingDB Entry DOI: 10.7270/Q2Q243Q0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50265621 (((1R,4S,5R)-4-(2,6-dimethoxy-4-(2-methyloctan-2-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica Curated by ChEMBL | Assay Description Agonist activity at human CB2 receptor expressed in HEK293 cell membranes assessed as induction of [35S]-GTPgammaS binding after 60 mins by liquid sc... | J Med Chem 59: 6753-6771 (2016) Article DOI: 10.1021/acs.jmedchem.6b00397 BindingDB Entry DOI: 10.7270/Q2Q243Q0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50265621 (((1R,4S,5R)-4-(2,6-dimethoxy-4-(2-methyloctan-2-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica Curated by ChEMBL | Assay Description Agonist activity at human CB2 receptor expressed in HEK293 cell membranes assessed as induction of [35S]-GTPgammaS binding after 60 mins by liquid sc... | J Med Chem 59: 6753-6771 (2016) Article DOI: 10.1021/acs.jmedchem.6b00397 BindingDB Entry DOI: 10.7270/Q2Q243Q0 | |||||||||||
More data for this Ligand-Target Pair |