Found 4 hits Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM50382752' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50382752
(CHEMBL2023580)Show SMILES OC(=O)c1cnc(NC(=O)c2cc3CCCCCCc3n(CC3CCCCC3)c2=O)s1 Show InChI InChI=1S/C23H29N3O4S/c27-20(25-23-24-13-19(31-23)22(29)30)17-12-16-10-6-1-2-7-11-18(16)26(21(17)28)14-15-8-4-3-5-9-15/h12-13,15H,1-11,14H2,(H,29,30)(H,24,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 885 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Binding affinity to CB2 receptor (unknown origin) |
Eur J Med Chem 93: 16-32 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50382752
(CHEMBL2023580)Show SMILES OC(=O)c1cnc(NC(=O)c2cc3CCCCCCc3n(CC3CCCCC3)c2=O)s1 Show InChI InChI=1S/C23H29N3O4S/c27-20(25-23-24-13-19(31-23)22(29)30)17-12-16-10-6-1-2-7-11-18(16)26(21(17)28)14-15-8-4-3-5-9-15/h12-13,15H,1-11,14H2,(H,29,30)(H,24,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 885 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Binding affinity to CB2 receptor (unknown origin) |
Eur J Med Chem 93: 16-32 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50382752
(CHEMBL2023580)Show SMILES OC(=O)c1cnc(NC(=O)c2cc3CCCCCCc3n(CC3CCCCC3)c2=O)s1 Show InChI InChI=1S/C23H29N3O4S/c27-20(25-23-24-13-19(31-23)22(29)30)17-12-16-10-6-1-2-7-11-18(16)26(21(17)28)14-15-8-4-3-5-9-15/h12-13,15H,1-11,14H2,(H,29,30)(H,24,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 885 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi& Co., Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor membrane fractions |
Bioorg Med Chem Lett 22: 2898-901 (2012)
Article DOI: 10.1016/j.bmcl.2012.02.050
BindingDB Entry DOI: 10.7270/Q2Q81F30 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50382752
(CHEMBL2023580)Show SMILES OC(=O)c1cnc(NC(=O)c2cc3CCCCCCc3n(CC3CCCCC3)c2=O)s1 Show InChI InChI=1S/C23H29N3O4S/c27-20(25-23-24-13-19(31-23)22(29)30)17-12-16-10-6-1-2-7-11-18(16)26(21(17)28)14-15-8-4-3-5-9-15/h12-13,15H,1-11,14H2,(H,29,30)(H,24,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi& Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as increase in forskolin-induced cAMP levels after 20 mins |
Bioorg Med Chem Lett 22: 2898-901 (2012)
Article DOI: 10.1016/j.bmcl.2012.02.050
BindingDB Entry DOI: 10.7270/Q2Q81F30 |
More data for this
Ligand-Target Pair | |
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