Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Capsid protein (Hepatitis B virus) | BDBM324416 (US10189835, Compound 594) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo... | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128353 BindingDB Entry DOI: 10.7270/Q25H7M64 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Capsid protein (Hepatitis B virus genotype C subtype ayr (isolate ...) | BDBM324416 (US10189835, Compound 594) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
NOVIRA THERAPEUTICS, INC. US Patent | Assay Description HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int... | US Patent US10189835 (2019) BindingDB Entry DOI: 10.7270/Q2KP8482 | |||||||||||
More data for this Ligand-Target Pair |