BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Capsid protein' and Ligand = 'BDBM324425'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Capsid protein (Hepatitis B virus)	BDBM324425 (US10189835, Compound 910) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128353 BindingDB Entry DOI: 10.7270/Q25H7M64
TBA					More data for this Ligand-Target Pair
Capsid protein (Hepatitis B virus genotype C subtype ayr (isolate ...)	BDBM324425 (US10189835, Compound 910) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
NOVIRA THERAPEUTICS, INC. US Patent					Assay Description HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...				US Patent US10189835 (2019) BindingDB Entry DOI: 10.7270/Q2KP8482
NOVIRA THERAPEUTICS, INC. US Patent					More data for this Ligand-Target Pair