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Found 1 hit Enz. Inhib. hit(s) with Target = 'Carbonic Anhydrase 2 (Can2)' and Ligand = 'BDBM50339592'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic Anhydrase 2 (Can2)


(Cryptococcus neoformans var. grubii (Filobasidiell...)
BDBM50339592
PNG
(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Show SMILES COc1cc(C=C2N=C(N)NC2=O)ccc1O |w:5.4,t:7|
Show InChI InChI=1S/C11H11N3O3/c1-17-9-5-6(2-3-8(9)15)4-7-10(16)14-11(12)13-7/h2-5,15H,1H3,(H3,12,13,14,16)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
890n/an/an/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay


J Med Chem 54: 1682-92 (2011)


Article DOI: 10.1021/jm1013242
More data for this
Ligand-Target Pair