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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Carbonic Anhydrase XIV' and Ligand = 'BDBM50167327'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic Anhydrase XIV


(Homo sapiens (Human))
BDBM50167327
PNG
(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Show SMILES NS(=O)(=O)c1ccc(CNc2nc(Cl)nc(NCC(O)=O)n2)cc1
Show InChI InChI=1S/C12H13ClN6O4S/c13-10-17-11(19-12(18-10)16-6-9(20)21)15-5-7-1-3-8(4-2-7)24(14,22)23/h1-4H,5-6H2,(H,20,21)(H2,14,22,23)(H2,15,16,17,18,19)
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PC cid
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Article
PubMed
9.30n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration method


Bioorg Med Chem 19: 3105-19 (2011)


Article DOI: 10.1016/j.bmc.2011.04.005
BindingDB Entry DOI: 10.7270/Q2FF3SQ6
More data for this
Ligand-Target Pair