BindingDB PrimarySearch

Found 10 hits Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase' and Ligand = 'BDBM26999'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase (Sulfurihydrogenibium sp. (strain YO3AOP1))	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assay				Bioorg Med Chem Lett 26: 401-5 (2016) Article DOI: 10.1016/j.bmcl.2015.11.104 BindingDB Entry DOI: 10.7270/Q2DB83QG
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Stylophora pistillata)	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	45.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MC-98000 Princ Curated by ChEMBL					Assay Description Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assay				Bioorg Med Chem 17: 5054-8 (2009) Article DOI: 10.1016/j.bmc.2009.05.063 BindingDB Entry DOI: 10.7270/Q2FJ2HQJ
MC-98000 Princ Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Stylophora pistillata)	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	45.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre Scientifique de Monaco Curated by ChEMBL					Assay Description Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay				Bioorg Med Chem Lett 21: 710-4 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2010.11.124 BindingDB Entry DOI: 10.7270/Q26D5T7K
Centre Scientifique de Monaco Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Stylophora pistillata)	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre Scientifique de Monaco Curated by ChEMBL					Assay Description Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay				Bioorg Med Chem Lett 21: 710-4 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2010.11.124 BindingDB Entry DOI: 10.7270/Q26D5T7K
Centre Scientifique de Monaco Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Anopheles gambiae)	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	265	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere and Tampere University Hospital Curated by ChEMBL					Assay Description Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assay				Bioorg Med Chem 23: 2303-9 (2015) Article DOI: 10.1016/j.bmc.2015.03.081 BindingDB Entry DOI: 10.7270/Q2TX3H2M
					More data for this Ligand-Target Pair
Carbonic anhydrase (Astrosclera willeyana)	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration...				Bioorg Med Chem 20: 1403-10 (2012) Article DOI: 10.1016/j.bmc.2012.01.007 BindingDB Entry DOI: 10.7270/Q2VH5P89
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Cryptococcus neoformans var. grubii (Filobasidiell...)	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				Bioorg Med Chem 17: 4503-9 (2009) Article DOI: 10.1016/j.bmc.2009.05.002 BindingDB Entry DOI: 10.7270/Q24X564B
Universite degli Studi di Firenze					More data for this Ligand-Target Pair
Carbonic anhydrase (Saccharomyces cerevisiae)	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Balikesir University Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assay				Bioorg Med Chem 17: 1158-63 (2009) Article DOI: 10.1016/j.bmc.2008.12.035 BindingDB Entry DOI: 10.7270/Q2FB53WW
Balikesir University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Candida albicans (Yeast))	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				Bioorg Med Chem 17: 4503-9 (2009) Article DOI: 10.1016/j.bmc.2009.05.002 BindingDB Entry DOI: 10.7270/Q24X564B
Universite degli Studi di Firenze					More data for this Ligand-Target Pair
Carbonic anhydrase (Mycobacterium tuberculosis)	BDBM26999 (4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	6.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kochi Medical School					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				J Med Chem 52: 3116-20 (2009) Article DOI: 10.1021/jm9003126 BindingDB Entry DOI: 10.7270/Q28G8J2G
Kochi Medical School					More data for this Ligand-Target Pair