Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Carbonic anhydrase (Saccharomyces cerevisiae) | BDBM29277 (CHEMBL451332 | sulfonamide, 3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 165 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assay | Bioorg Med Chem 17: 1158-63 (2009) Article DOI: 10.1016/j.bmc.2008.12.035 BindingDB Entry DOI: 10.7270/Q2FB53WW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Stylophora pistillata) | BDBM29277 (CHEMBL451332 | sulfonamide, 3) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 256 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre Scientifique de Monaco Curated by ChEMBL | Assay Description Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay | Bioorg Med Chem Lett 21: 710-4 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2010.11.124 BindingDB Entry DOI: 10.7270/Q26D5T7K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Stylophora pistillata) | BDBM29277 (CHEMBL451332 | sulfonamide, 3) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 256 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
MC-98000 Princ Curated by ChEMBL | Assay Description Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assay | Bioorg Med Chem 17: 5054-8 (2009) Article DOI: 10.1016/j.bmc.2009.05.063 BindingDB Entry DOI: 10.7270/Q2FJ2HQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Stylophora pistillata) | BDBM29277 (CHEMBL451332 | sulfonamide, 3) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 294 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre Scientifique de Monaco Curated by ChEMBL | Assay Description Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay | Bioorg Med Chem Lett 21: 710-4 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2010.11.124 BindingDB Entry DOI: 10.7270/Q26D5T7K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Cryptococcus neoformans var. grubii (Filobasidiell...) | BDBM29277 (CHEMBL451332 | sulfonamide, 3) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 17: 4503-9 (2009) Article DOI: 10.1016/j.bmc.2009.05.002 BindingDB Entry DOI: 10.7270/Q24X564B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Candida albicans (Yeast)) | BDBM29277 (CHEMBL451332 | sulfonamide, 3) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.28E+3 | -33.1 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Universite degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 17: 4503-9 (2009) Article DOI: 10.1016/j.bmc.2009.05.002 BindingDB Entry DOI: 10.7270/Q24X564B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Mycobacterium tuberculosis) | BDBM29277 (CHEMBL451332 | sulfonamide, 3) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.83E+3 | -28.7 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Kochi Medical School | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | J Med Chem 52: 3116-20 (2009) Article DOI: 10.1021/jm9003126 BindingDB Entry DOI: 10.7270/Q28G8J2G | |||||||||||
More data for this Ligand-Target Pair |