Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM33280 (CHEMBL153094 | aliphatic sulfamate, 2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 530 | -35.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 23 |
CNR | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | J Med Chem 52: 5990-8 (2009) Article DOI: 10.1021/jm900641r BindingDB Entry DOI: 10.7270/Q2GF0RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM33280 (CHEMBL153094 | aliphatic sulfamate, 2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Montpellier II Curated by ChEMBL | Assay Description Inhibitory activity against human carbonic anhydrase I. | J Med Chem 46: 5471-7 (2003) Article DOI: 10.1021/jm030911u BindingDB Entry DOI: 10.7270/Q2KP81KV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM33280 (CHEMBL153094 | aliphatic sulfamate, 2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Montpellier II Curated by ChEMBL | Assay Description Inhibitory activity against human carbonic anhydrase I. | J Med Chem 46: 5471-7 (2003) Article DOI: 10.1021/jm030911u BindingDB Entry DOI: 10.7270/Q2KP81KV | |||||||||||
More data for this Ligand-Target Pair |