Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50314771 (4-((2R,3R,4R,5R)-3,4,5-trihydroxytetrahydro-2H-pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier II Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase I | Bioorg Med Chem Lett 14: 225-9 (2003) BindingDB Entry DOI: 10.7270/Q2WD414J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50314771 (4-((2R,3R,4R,5R)-3,4,5-trihydroxytetrahydro-2H-pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 840 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universit£ Montpellier II Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5 | Bioorg Med Chem 19: 1172-8 (2011) Article DOI: 10.1016/j.bmc.2010.12.048 BindingDB Entry DOI: 10.7270/Q2C53M44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50314771 (4-((2R,3R,4R,5R)-3,4,5-trihydroxytetrahydro-2H-pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human recombinant carbonic anhydrase1 after 15 mins by stopped flow carbondioxide hydrase assay method | Bioorg Med Chem Lett 20: 2178-82 (2010) Article DOI: 10.1016/j.bmcl.2010.02.042 BindingDB Entry DOI: 10.7270/Q2KP829P | |||||||||||
More data for this Ligand-Target Pair |