new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 12' and Ligand = 'BDBM50190238'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50190238
PNG
(2-(aminosulfonyl)-5-chloro-4-methylphenyl -N-(4-ni...)
Show SMILES CCC(Sc1cc(Cl)c(C)cc1S(N)(=O)=O)=NNc1ccc(cc1)[N+]([O-])=O |w:16.17|
Show InChI InChI=1S/C16H17ClN4O4S2/c1-3-16(20-19-11-4-6-12(7-5-11)21(22)23)26-14-9-13(17)10(2)8-15(14)27(18,24)25/h4-9,19H,3H2,1-2H3,(H2,18,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Medical University of Gdansk

Curated by ChEMBL


Assay Description
Inhibition of human cloned CA12 catalytic domain by CO2 hydration assay


Bioorg Med Chem Lett 16: 4846-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.064
BindingDB Entry DOI: 10.7270/Q2794493
More data for this
Ligand-Target Pair