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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM246507'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))		BDBM246507
PNG
(1-(4-Fluorophenyl)-3-(4-(1,3,7,7-tetramethyl-5-oxo...)
Show SMILES CN1C(C2=C(CC(C)(C)CC2=O)N(C)C1=O)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1 |t:3|
Show InChI InChI=1S/C25H27FN4O3/c1-25(2)13-19-21(20(31)14-25)22(30(4)24(33)29(19)3)15-5-9-17(10-6-15)27-23(32)28-18-11-7-16(26)8-12-18/h5-12,22H,13-14H2,1-4H3,(H2,27,28,32)
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Article
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n/an/a 1.42E+5n/an/an/an/an/an/a



Sakarya University



Assay Description
For the inhibition studies of sulphanilamide, different concentrationsof these compounds were added to the enzyme. Activity percentage values of CA f...

J Enzyme Inhib Med Chem 29: 18-22 (2014)


Article DOI: 10.3109/14756366.2012.746972
BindingDB Entry DOI: 10.7270/Q28S4NVM
More data for this
Ligand-Target Pair