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Found 1 hit Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM50093555'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))		BDBM50093555
PNG
(CHEMBL3585757)
Show SMILES CCOc1ccc(cc1-c1nnc2n(nc(C)c2n1)-c1ccc(Cl)cc1)S(=O)(=O)N1CCN(C)CC1
Show InChI InChI=1S/C24H26ClN7O3S/c1-4-35-21-10-9-19(36(33,34)31-13-11-30(3)12-14-31)15-20(21)23-26-22-16(2)29-32(24(22)28-27-23)18-7-5-17(25)6-8-18/h5-10,15H,4,11-14H2,1-3H3
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PC cid
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UniChem
Article
PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase-2 pre-incubated for 15 mins by stopped-flow CO2 hydration assay based Lineweaver-Burk plot method

Bioorg Med Chem 23: 3674-80 (2015)


Article DOI: 10.1016/j.bmc.2015.04.011
BindingDB Entry DOI: 10.7270/Q2SJ1NCF
More data for this
Ligand-Target Pair