Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM10862 (4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Agricultural Sciences and Veterinary Medicine | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | J Med Chem 46: 2187-96 (2003) Article DOI: 10.1021/jm021123s BindingDB Entry DOI: 10.7270/Q2XK8CR9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM10862 (4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibitory activity against human cloned carbonic anhydrase isozyme IX, by CO2 hydrase assay method. | Bioorg Med Chem Lett 13: 1005-9 (2003) BindingDB Entry DOI: 10.7270/Q2PV6KXV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM10862 (4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Laxmi Fumigation and Pest Control (P) Curated by ChEMBL | Assay Description Inhibitory activity against human tumor-associated transmembrane carbonic anhydrase IX. | Bioorg Med Chem Lett 14: 3283-90 (2004) Article DOI: 10.1016/j.bmcl.2004.03.099 BindingDB Entry DOI: 10.7270/Q2K074TZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM10862 (4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kochi Medical School Curated by ChEMBL | Assay Description Inhibition of catalytic domain of human recombinant CA IX | J Med Chem 50: 381-8 (2007) Article DOI: 10.1021/jm0612057 BindingDB Entry DOI: 10.7270/Q29G5NNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM10862 (4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kochi Medical School Curated by ChEMBL | Assay Description Inhibitory constant against catalytic domain of human carbonic anhydrase IX | Bioorg Med Chem Lett 15: 3828-33 (2005) Article DOI: 10.1016/j.bmcl.2005.06.055 BindingDB Entry DOI: 10.7270/Q2C82B2K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM10862 (4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tampere Curated by ChEMBL | Assay Description Inhibitory activity against human carbonic anhydrase IX (hCA IX) by using CO2 hydrase assay method | Bioorg Med Chem Lett 14: 3757-62 (2004) Article DOI: 10.1016/j.bmcl.2004.04.106 BindingDB Entry DOI: 10.7270/Q24Q7VJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM10862 (4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-flu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Inhibitory activity against human carbonic anhydrase IX at 0.09 uM | Bioorg Med Chem Lett 14: 6001-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.085 BindingDB Entry DOI: 10.7270/Q23X87D5 | |||||||||||
More data for this Ligand-Target Pair |