BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Carbonyl reductase [NADPH] 1' and Ligand = 'BDBM50247677'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50247677 ((3S,8S)-14,16-dihydroxy-3,8-dimethyl-3,4,5,6,9,10-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50247677 ((3S,8S)-14,16-dihydroxy-3,8-dimethyl-3,4,5,6,9,10-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate				Bioorg Med Chem 17: 530-6 (2009) Article DOI: 10.1016/j.bmc.2008.11.076 BindingDB Entry DOI: 10.7270/Q2SJ1KFH
Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair