Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carnitine O-palmitoyltransferase 1, liver isoform (Homo sapiens (Human)) | BDBM50122839 (CHEMBL106227 | [3-Carboxy-2-(3-tetradecyl-ureido)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition of human CPT1A | J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carnitine O-palmitoyltransferase 1, liver isoform (Rattus norvegicus) | BDBM50122839 (CHEMBL106227 | [3-Carboxy-2-(3-tetradecyl-ureido)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL | Assay Description Inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I from rat liver mitochondria | J Med Chem 46: 303-9 (2003) Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM | |||||||||||
More data for this Ligand-Target Pair |