Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase I isoform alpha (Homo sapiens (Human)) | BDBM25017 (2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter | Eur J Med Chem 56: 30-38 (2012) Article DOI: 10.1016/j.ejmech.2012.08.007 BindingDB Entry DOI: 10.7270/Q2FJ2J2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha (Homo sapiens (Human)) | BDBM25017 (2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee | Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] labe... | Biochem J 401: 29-38 (2007) Article DOI: 10.1042/BJ20061088 BindingDB Entry DOI: 10.7270/Q25Q4TD7 | |||||||||||
More data for this Ligand-Target Pair |