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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cdc7 Kinase' and Ligand = 'BDBM27350'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cdc7 Kinase


(Homo sapiens (Human))
BDBM27350
PNG
(6-[(benzyloxy)methyl]-2-(pyridin-4-yl)-1H,4H,5H,6H...)
Show SMILES O=C1NC(COCc2ccccc2)Cc2[nH]c(cc12)-c1ccncc1
Show InChI InChI=1S/C20H19N3O2/c24-20-17-11-18(15-6-8-21-9-7-15)23-19(17)10-16(22-20)13-25-12-14-4-2-1-3-5-14/h1-9,11,16,23H,10,12-13H2,(H,22,24)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 44n/an/an/an/a7.925



Nerviano Medical Sciences Srl



Assay Description
The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...


J Med Chem 52: 293-307 (2009)


Article DOI: 10.1021/jm800977q
BindingDB Entry DOI: 10.7270/Q27W69JX
More data for this
Ligand-Target Pair