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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cdc7 Kinase' and Ligand = 'BDBM27405'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cdc7 Kinase


(Homo sapiens (Human))
BDBM27405
PNG
(2-(2-aminopyrimidin-4-yl)-1-(2-hydroxyethyl)-1H,4H...)
Show SMILES Nc1nccc(n1)-c1cc2c(CCNC2=O)n1CCO
Show InChI InChI=1S/C13H15N5O2/c14-13-16-3-1-9(17-13)11-7-8-10(18(11)5-6-19)2-4-15-12(8)20/h1,3,7,19H,2,4-6H2,(H,15,20)(H2,14,16,17)
PDB

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UniProtKB/SwissProt

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antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 138n/an/an/an/a7.925



Nerviano Medical Sciences Srl



Assay Description
The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...


J Med Chem 51: 487-501 (2008)


Article DOI: 10.1021/jm700956r
BindingDB Entry DOI: 10.7270/Q247485B
More data for this
Ligand-Target Pair