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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cdc7 Kinase' and Ligand = 'BDBM27408'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cdc7 Kinase


(Homo sapiens (Human))
BDBM27408
PNG
(2-(2-aminopyrimidin-4-yl)-1-(propan-2-yl)-1H,4H,5H...)
Show SMILES CC(C)n1c2CCNC(=O)c2cc1-c1ccnc(N)n1
Show InChI InChI=1S/C14H17N5O/c1-8(2)19-11-4-6-16-13(20)9(11)7-12(19)10-3-5-17-14(15)18-10/h3,5,7-8H,4,6H2,1-2H3,(H,16,20)(H2,15,17,18)
PDB

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UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 42n/an/an/an/a7.925



Nerviano Medical Sciences Srl



Assay Description
The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...


J Med Chem 51: 487-501 (2008)


Article DOI: 10.1021/jm700956r
BindingDB Entry DOI: 10.7270/Q247485B
More data for this
Ligand-Target Pair