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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cdc7 Kinase' and Ligand = 'BDBM27419'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cdc7 Kinase


(Homo sapiens (Human))
BDBM27419
PNG
(2-[2-(propylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...)
Show SMILES CCCNc1nccc(n1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C14H17N5O/c1-2-5-16-14-17-7-4-11(19-14)12-8-9-10(18-12)3-6-15-13(9)20/h4,7-8,18H,2-3,5-6H2,1H3,(H,15,20)(H,16,17,19)
PDB

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UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 259n/an/an/an/an/an/a



Nerviano Medical Sciences Srl



Assay Description
The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...


J Med Chem 51: 487-501 (2008)


Article DOI: 10.1021/jm700956r
BindingDB Entry DOI: 10.7270/Q247485B
More data for this
Ligand-Target Pair