Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Cereblon isoform 4' and Ligand = 'BDBM50070114'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon isoform 4 (Magnetospirillum gryphiswaldense)	BDBM50070114 ((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...) Show SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)c2ccccc12 Show InChI InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute for Developmental Biology Curated by ChEMBL					Assay Description Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by Cheng-Prusoff equation analysis				J Med Chem 59: 770-4 (2016) Article DOI: 10.1021/acs.jmedchem.5b01735 BindingDB Entry DOI: 10.7270/Q2PR7XVF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cereblon isoform 4 (Magnetospirillum gryphiswaldense)	BDBM50070114 ((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...) Show SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)c2ccccc12 Show InChI InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute for Developmental Biology Curated by ChEMBL					Assay Description Inhibition of MANT-uracil binding to wild-type Magnetospirillum gryphiswaldense CRBN isoform 4 by FRET assay				J Med Chem 62: 6615-6629 (2019) Article DOI: 10.1021/acs.jmedchem.9b00454 BindingDB Entry DOI: 10.7270/Q2JH3QK6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cereblon isoform 4 (Magnetospirillum gryphiswaldense)	BDBM50070114 ((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...) Show SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)c2ccccc12 Show InChI InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute for Developmental Biology Curated by ChEMBL					Assay Description Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by FRET assay				J Med Chem 59: 770-4 (2016) Article DOI: 10.1021/acs.jmedchem.5b01735 BindingDB Entry DOI: 10.7270/Q2PR7XVF
					More data for this Ligand-Target Pair				3D Structure (crystal)