new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chemokine receptor type 1 (CXCR1)' and Ligand = 'BDBM50248113'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chemokine receptor type 1 (CXCR1)


(Homo sapiens (Human))
BDBM50248113
PNG
((R)-N-(2-cyanoethyl)-3-(4-(2,2-dimethyl-1-(5-methy...)
Show SMILES CN(CCC#N)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccc(C)o2)C(C)(C)C)c1O |r|
Show InChI InChI=1S/C23H28N6O3S/c1-14-10-11-17(32-14)19(23(2,3)4)26-21-20(27-33-28-21)25-16-9-6-8-15(18(16)30)22(31)29(5)13-7-12-24/h6,8-11,19,30H,7,13H2,1-5H3,(H,25,27)(H,26,28)/t19-/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
13n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of IL8 from CXCR1 receptor (unknown origin)


Bioorg Med Chem Lett 19: 1434-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.027
BindingDB Entry DOI: 10.7270/Q2833RW1
More data for this
Ligand-Target Pair