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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM50199161'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholinesterase


(Equus caballus (Horse))		BDBM50199161
PNG
(CHEMBL3961411)
Show SMILES CN(C)Cc1ccc(CSCCNc2nnc(c(C)c2[N+]([O-])=O)-c2ccccc2)o1
Show InChI InChI=1S/C21H25N5O3S/c1-15-19(16-7-5-4-6-8-16)23-24-21(20(15)26(27)28)22-11-12-30-14-18-10-9-17(29-18)13-25(2)3/h4-10H,11-14H2,1-3H3,(H,22,24)
PDB

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 3.71E+3n/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of equine serum BuChE using butyrylthiocholine as substrate preincubated for 8 mins followed by substrate addition by Ellman's method

Bioorg Med Chem Lett 26: 5573-5579 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.072
BindingDB Entry DOI: 10.7270/Q22F7QDF
More data for this
Ligand-Target Pair