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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Inhibition of Equine Butyrylcholinesterase | J Med Chem 46: 1-4 (2002) Article DOI: 10.1021/jm0255668 BindingDB Entry DOI: 10.7270/Q2GF0V7X | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi della Magna Gr£cia Viale Europa Curated by ChEMBL | Assay Description Non-competitive inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analysis | ACS Med Chem Lett 7: 470-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00483 BindingDB Entry DOI: 10.7270/Q2PN97JV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 6.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
COMSATS Institute of Information Technology | Assay Description Inhibition assay using AChE and BuChE. | Chem Biol Drug Des 80: 605-15 (2012) Article DOI: 10.1111/j.1747-0285.2012.01435.x BindingDB Entry DOI: 10.7270/Q28P5Z3T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Banaras Hindu University Curated by ChEMBL | Assay Description Non competitive inhibition of human serum BChE using butyrylthiocholine iodide as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 5451-60 (2013) Article DOI: 10.1016/j.bmc.2013.06.003 BindingDB Entry DOI: 10.7270/Q27W6DM2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to... | Eur J Med Chem 139: 48-59 (2017) Article DOI: 10.1016/j.ejmech.2017.07.055 BindingDB Entry DOI: 10.7270/Q2GM89X1 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute Curated by ChEMBL | Assay Description Inhibition of human Cholinesterase | Bioorg Med Chem 27: 895-930 (2019) Article DOI: 10.1016/j.bmc.2019.01.025 BindingDB Entry DOI: 10.7270/Q2N87F3N | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-i-Azam University Curated by ChEMBL | Assay Description Inhibition of human BChE by Ellman's method | Bioorg Med Chem 22: 6163-73 (2014) Article DOI: 10.1016/j.bmc.2014.08.026 BindingDB Entry DOI: 10.7270/Q2JQ12M3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human BuChe using S-butyrylthiocholine iodide as substrate measured after 7 mins by Ellman's method | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113541 BindingDB Entry DOI: 10.7270/Q25D8WNM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gujrat Curated by ChEMBL | Assay Description Inhibition of butyrylcholinesterase (unknown origin) using butyrylthiocholine chloride as substrate incubated for 10 mins followed by substrate addit... | Bioorg Med Chem 25: 100-106 (2017) Article DOI: 10.1016/j.bmc.2016.10.016 BindingDB Entry DOI: 10.7270/Q2B85B3V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gujrat Curated by ChEMBL | Assay Description Inhibition of horse serum BChE using butyrylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition measured after 20 m... | Bioorg Med Chem 26: 3696-3706 (2018) Article DOI: 10.1016/j.bmc.2018.05.050 BindingDB Entry DOI: 10.7270/Q2V69N32 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 231 | n/a | n/a | n/a | n/a | n/a | n/a |
Mansoura University Curated by ChEMBL | Assay Description Inhibition of horse serum BuChE using acetylthiocholine as substrate by UV-visible spectrophotometric Ellman's method | Bioorg Med Chem Lett 28: 2910-2913 (2018) Article DOI: 10.1016/j.bmcl.2018.07.019 BindingDB Entry DOI: 10.7270/Q2R21422 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Tehran University of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 ... | Bioorg Med Chem 26: 4952-4962 (2018) Article DOI: 10.1016/j.bmc.2018.08.035 BindingDB Entry DOI: 10.7270/Q2NS0XJS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Tehran University of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m... | Eur J Med Chem 155: 49-60 (2018) Article DOI: 10.1016/j.ejmech.2018.05.031 BindingDB Entry DOI: 10.7270/Q2765HWM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Ataturk University Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins by Ellman's method | Bioorg Med Chem Lett 25: 5576-82 (2015) Article DOI: 10.1016/j.bmcl.2015.10.051 BindingDB Entry DOI: 10.7270/Q2J67JQB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Autonoma de Madrid Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE by Ellman's method | J Med Chem 53: 5129-43 (2010) Article DOI: 10.1021/jm901902w BindingDB Entry DOI: 10.7270/Q25T3MFV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratorio de Qu�mica M�dica (IQOG, CSIC) Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ... | Eur J Med Chem 75: 82-95 (2014) Article DOI: 10.1016/j.ejmech.2013.12.028 BindingDB Entry DOI: 10.7270/Q22R3T4P | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratori de Qu�mica Farmac�utica (Unitat Associada al CSIC) Curated by ChEMBL | Assay Description Inhibition of human serum BChE by Ellman's assay | J Med Chem 51: 3588-98 (2008) Article DOI: 10.1021/jm8001313 BindingDB Entry DOI: 10.7270/Q2F76DGK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuropharma | Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with... | Bioorg Med Chem 13: 6588-97 (2005) Article DOI: 10.1016/j.bmc.2005.09.029 BindingDB Entry DOI: 10.7270/Q2G73BW9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 941 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology (Banaras Hindu University) Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured fo... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111613 BindingDB Entry DOI: 10.7270/Q2GQ726C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BuChE in human serum using butyrylthiocholineiodide as substrate pre-incubated for 10 mins followed by substrate addition and measured ... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113224 BindingDB Entry DOI: 10.7270/Q2HM5D5K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Maharaja Sayajirao University of Baroda Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using BTCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman ass... | J Med Chem 59: 5823-46 (2016) Article DOI: 10.1021/acs.jmedchem.6b00426 BindingDB Entry DOI: 10.7270/Q2SJ1Q44 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi della Magna Gr£cia Viale Europa Curated by ChEMBL | Assay Description Inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Ellman method | ACS Med Chem Lett 7: 470-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00483 BindingDB Entry DOI: 10.7270/Q2PN97JV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant equine BChE by Ellman's method | Citation and Details Article DOI: 10.1016/j.bmc.2021.116355 BindingDB Entry DOI: 10.7270/Q2JS9V7D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Mansoura University Curated by ChEMBL | Assay Description Inhibition of horse serum BuChE using acetylthiocholine as substrate after 60 mins by FRET assay | Bioorg Med Chem Lett 28: 2910-2913 (2018) Article DOI: 10.1016/j.bmcl.2018.07.019 BindingDB Entry DOI: 10.7270/Q2R21422 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology (Banaras Hindu University) Curated by ChEMBL | Assay Description Inhibition of human serum butyrylcholinesterase using BTCI as substrate pre-incubated for 10 mins followed by substrate addition and measured for 6 m... | Eur J Med Chem 167: 510-524 (2019) Article DOI: 10.1016/j.ejmech.2019.02.030 BindingDB Entry DOI: 10.7270/Q2JD5192 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Franche Comt£ Curated by ChEMBL | Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins prior to substrate challenge me... | Bioorg Med Chem 22: 2496-507 (2014) Article DOI: 10.1016/j.bmc.2014.02.046 BindingDB Entry DOI: 10.7270/Q28K7BMT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of BuChE in horse serum pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's assay | Bioorg Med Chem 23: 1629-37 (2015) Article DOI: 10.1016/j.bmc.2015.01.045 BindingDB Entry DOI: 10.7270/Q2PN979Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113783 BindingDB Entry DOI: 10.7270/Q21V5JSC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of equine serum BuChE using BTC as substrate preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's met... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113792 BindingDB Entry DOI: 10.7270/Q2514325 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mi... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113397 BindingDB Entry DOI: 10.7270/Q29S1VTT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Collegium Medicum Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE preincubated for 5 mins followed by butyrylthiocholine iodide substrate addition measured after 5 mins by Ellman's m... | Eur J Med Chem 124: 63-81 (2016) Article DOI: 10.1016/j.ejmech.2016.08.016 BindingDB Entry DOI: 10.7270/Q2PZ5BT8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate preincubated for 5 mins followed by substrate addition measured after ... | Bioorg Med Chem Lett 26: 4140-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.054 BindingDB Entry DOI: 10.7270/Q2XD155T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate preincubated for 5 mins followed by substrate addition measured after ... | Bioorg Med Chem Lett 26: 4140-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.054 BindingDB Entry DOI: 10.7270/Q2XD155T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 5 mins prior to substrate addition measured... | Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111785 BindingDB Entry DOI: 10.7270/Q2Q81HF9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate pre-incubated for 5 mins followed by substrate addition and measured ... | Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111916 BindingDB Entry DOI: 10.7270/Q2639T4N | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 5... | Eur J Med Chem 125: 676-695 (2017) Article DOI: 10.1016/j.ejmech.2016.09.078 BindingDB Entry DOI: 10.7270/Q22Z17QK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE after 5 mins by Ellman's method | Eur J Med Chem 92: 738-49 (2015) Article DOI: 10.1016/j.ejmech.2015.01.027 BindingDB Entry DOI: 10.7270/Q23T9JXZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL | Assay Description Inhibition of equine butyrylcholinesterase using butyrylthicholine as substrate incubated for 20 mins prior to substrate addition measured after 3 mi... | Bioorg Med Chem 21: 146-52 (2012) Article DOI: 10.1016/j.bmc.2012.10.045 BindingDB Entry DOI: 10.7270/Q2QV3NTH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Delhi Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate incubated for 5 mins by Ellman's method | Bioorg Med Chem 23: 1135-48 (2015) Article DOI: 10.1016/j.bmc.2014.12.057 BindingDB Entry DOI: 10.7270/Q2DJ5H90 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113278 BindingDB Entry DOI: 10.7270/Q2PR80XJ | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Mus musculus (Mouse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BuChE in mouse serum using butyrylthiocholine iodide as substrate incubated for 20 mins by Ellman's method | Citation and Details Article DOI: 10.1016/j.ejmech.2021.114045 BindingDB Entry DOI: 10.7270/Q29K4G4C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL | Assay Description Inhibition of butyrylcholinesterase (unknown origin) | Bioorg Med Chem 21: 146-52 (2012) Article DOI: 10.1016/j.bmc.2012.10.045 BindingDB Entry DOI: 10.7270/Q2QV3NTH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113278 BindingDB Entry DOI: 10.7270/Q2PR80XJ | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate by Ellman's method | Eur J Med Chem 161: 292-309 (2019) Article DOI: 10.1016/j.ejmech.2018.10.016 BindingDB Entry DOI: 10.7270/Q2X351QR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of horse serum BChE by Ellman's spectrophotometric assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01784 BindingDB Entry DOI: 10.7270/Q2BG2SWG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and ... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116385 BindingDB Entry DOI: 10.7270/Q28W3J18 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Porto Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 5 mins ... | Eur J Med Chem 174: 116-129 (2019) Article DOI: 10.1016/j.ejmech.2019.04.026 BindingDB Entry DOI: 10.7270/Q2KW5KFM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyung Hee University Curated by ChEMBL | Assay Description Inhibition of equine serum BCHE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m... | Bioorg Med Chem Lett 27: 1179-1185 (2017) Article DOI: 10.1016/j.bmcl.2017.01.068 BindingDB Entry DOI: 10.7270/Q2P271CH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari Aldo Moro Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine as substrate preincubated for 20 mins followed by substrate addition and measured upto 5 min... | Eur J Med Chem 177: 414-424 (2019) Article DOI: 10.1016/j.ejmech.2019.05.062 BindingDB Entry DOI: 10.7270/Q2RF5ZGP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m... | J Med Chem 59: 6791-806 (2016) Article DOI: 10.1021/acs.jmedchem.6b00562 BindingDB Entry DOI: 10.7270/Q25142Q8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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