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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 5' and Ligand = 'BDBM50194250'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chromobox protein homolog 5


(Homo sapiens (Human))
BDBM50194250
PNG
(CHEMBL3985510)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN1CCCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1/C43H63N7O9/c1-29(2)25-34(42(57)47-33(40(55)49-36(28-51)43(58)59-4)21-13-16-24-50-22-14-5-6-15-23-50)48-38(53)30(3)45-41(56)35(26-31-17-9-7-10-18-31)46-37(52)27-44-39(54)32-19-11-8-12-20-32/h7-12,17-20,29-30,33-36,51H,5-6,13-16,21-28H2,1-4H3,(H,44,54)(H,45,56)(H,46,52)(H,47,57)(H,48,53)(H,49,55)/t30-,33-,34-,35-,36-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
More data for this
Ligand-Target Pair